AFEGA® TMG / Trimethylglycine – 150 g Powder
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AFEGA® TMG / Trimethylglycine, 150 g, is a powder product for people who specifically want to use a methyl donor. TMG, also known as betaine, is particularly relevant in discussions about methylation, homocysteine metabolism and its practical addition to certain routines.
Many users explore TMG when they use NMN or other NAD+ precursors. The reasoning is that methyl groups may be needed during the processing of nicotinamide. This question is discussed in research but has not been conclusively resolved in every respect. TMG is often viewed as a practical accompanying component in this context.
Product details
- 150 g TMG / trimethylglycine powder
- Also known as betaine
Why some users are interested in TMG
TMG is known as a methyl donor. Methyl groups play a role in many biochemical processes, including methylation metabolism. TMG is therefore often mentioned in connection with homocysteine, methylation balance and certain supplement routines.
TMG in the context of NMN
In discussions about NMN, a common question is whether a higher intake of NAD+ precursors can affect the need for methyl groups. This provides a plausible reason why many users include TMG as an additional component. However, not every question on this subject has been conclusively resolved scientifically. TMG should therefore be viewed less as a strict requirement and more as a potentially useful accompanying component of certain routines.
The difference between TMG and betaine HCl
TMG, also called betaine, is the form mainly discussed as a methyl donor. Betaine HCl additionally contains hydrochloride and is used in a different context, primarily to support stomach acid. This product contains TMG without HCl.
Choosing this format
The powder format suits users who want to dose TMG flexibly and incorporate it into their existing routine. The 150 g pack is a practical size for planned regular use.
Dosage
For information on dosage, please see the related blog post by Dr. Peter Niehenke.
Who may be interested in this product?
- People who specifically want to use a methyl donor
- Users who want to understand TMG in the context of NMN or other NAD+ precursors
- Anyone who wants to dose trimethylglycine flexibly in powder form
Further information
More detailed information on TMG and other substances is available on the Facebook page run by the AFEGA Research Group.


