AFEGA® TMG / Trimethylglycine – 1 kg Powder

AFEGA® TMG / Trimethylglycine, supplied as 1 kg of powder, is intended for those who specifically want to use a methyl-group donor with flexible dosing. TMG, also known as Betaine, is especially interesting in connection with methylation, homocysteine metabolism, and the practical supplementation of certain routines.

Many users consider TMG particularly when using NMN or other NAD+ precursors. This is based on the idea that methyl groups may be required when nicotinamide is metabolised. This question is discussed in research, but not every aspect has been conclusively resolved. In this context, TMG is often viewed as a practical addition.

Product data

• 1 kg TMG / Trimethylglycine powder
• also known as Betaine

Why some users may consider TMG

TMG is known as a methyl group donor. Methyl groups play a role in many biochemical processes, including methylation pathways. TMG is therefore often mentioned in relation to homocysteine, methylation balance and certain supplement routines.

Context in relation to NMN

In discussions about NMN, a recurring question is whether higher intake of NAD+ precursors can affect the need for methyl groups. This is a plausible reason why many users consider adding TMG to their routine. At the same time, not every question about this has been conclusively resolved by research. TMG should therefore be viewed as a potentially useful addition to certain routines rather than as a strict requirement.

TMG and Betaine HCl – the difference

TMG or Betaine is the form that is mainly discussed as a methyl group donor. Betaine HCl additionally contains hydrochloride and is used in a different context, namely primarily to support stomach acid. This product contains TMG without HCl.

Why choose the bulk pack

The 1 kg package is intended for users who want flexible dosing and plan to include TMG in their routine over the long term. The large package substantially reduces the need to reorder and is particularly suitable for people who deliberately prefer powder to capsules.

Dosage

Regarding dosing, please refer to the related BLOG post by Dr. Peter Niehenke.

Why we do not include measuring spoons

Some customers expect powder products to include a measuring spoon. We deliberately refrain from this: powders differ in their bulk density and grain size. These properties can also vary between batches of the same product. The same spoon volume therefore does not always correspond to the same amount of powder.

Since many customers use several powder products, different similar-looking measuring spoons can quickly accumulate. This can easily lead to confusion in everyday use.

For the most accurate dosing, we therefore recommend a suitable digital precision scale with a resolution matching the specified dosing amount. Such scales are available at affordable prices.

Who this product may suit

• for people who want to work specifically with a methyl group donor
• for users who want to understand TMG in relation to NMN or other NAD+ precursors
• for everyone who wants to dose trimethylglycine flexibly in powder form

Further information

More detailed information about TMG and other substances can be found on the AFEGA Research Group operated Facebook page.